Epigenetic silencing of the 3p22 tumor suppressor DLEC1 by promoter CpG methylation in non-Hodgkin and Hodgkin lymphomas

BACKGROUND: Inactivaion of tumor suppressor genes (TSGs) by promoter CpG methylation frequently occurs in tumorigenesis, even in the early stages, contributing to the initiation and progression of human cancers. Deleted in lung and esophageal cancer 1 (DLEC1), located at the 3p22-21.3 TSG cluster, h...

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Detalles Bibliográficos
Autores principales: Wang, Zhaohui, Li, Lili, Su, Xianwei, Gao, Zifen, Srivastava, Gopesh, Murray, Paul G, Ambinder, Richard, Tao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540012/
https://www.ncbi.nlm.nih.gov/pubmed/23050586
http://dx.doi.org/10.1186/1479-5876-10-209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540012/
https://www.ncbi.nlm.nih.gov/pubmed/23050586
http://dx.doi.org/10.1186/1479-5876-10-209

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