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Epigenetic silencing of the 3p22 tumor suppressor DLEC1 by promoter CpG methylation in non-Hodgkin and Hodgkin lymphomas
BACKGROUND: Inactivaion of tumor suppressor genes (TSGs) by promoter CpG methylation frequently occurs in tumorigenesis, even in the early stages, contributing to the initiation and progression of human cancers. Deleted in lung and esophageal cancer 1 (DLEC1), located at the 3p22-21.3 TSG cluster, h...
Autores principales: | Wang, Zhaohui, Li, Lili, Su, Xianwei, Gao, Zifen, Srivastava, Gopesh, Murray, Paul G, Ambinder, Richard, Tao, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540012/ https://www.ncbi.nlm.nih.gov/pubmed/23050586 http://dx.doi.org/10.1186/1479-5876-10-209 |
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