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Perlecan Maintains Microvessel Integrity In Vivo and Modulates Their Formation In Vitro

Perlecan is a heparan sulfate proteoglycan assembled into the vascular basement membranes (BMs) during vasculogenesis. In the present study we have investigated vessel formation in mice, teratomas and embryoid bodies (EBs) in the absence of perlecan. We found that perlecan was dispensable for blood...

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Detalles Bibliográficos
Autores principales: Gustafsson, Erika, Almonte-Becerril, Maylin, Bloch, Wilhelm, Costell, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540034/
https://www.ncbi.nlm.nih.gov/pubmed/23320101
http://dx.doi.org/10.1371/journal.pone.0053715