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Perlecan Maintains Microvessel Integrity In Vivo and Modulates Their Formation In Vitro
Perlecan is a heparan sulfate proteoglycan assembled into the vascular basement membranes (BMs) during vasculogenesis. In the present study we have investigated vessel formation in mice, teratomas and embryoid bodies (EBs) in the absence of perlecan. We found that perlecan was dispensable for blood...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540034/ https://www.ncbi.nlm.nih.gov/pubmed/23320101 http://dx.doi.org/10.1371/journal.pone.0053715 |