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High Throughput Phenotypic Selection of Mycobacterium tuberculosis Mutants with Impaired Resistance to Reactive Oxygen Species Identifies Genes Important for Intracellular Growth

Mycobacterium tuberculosis has the remarkable capacity to survive within the hostile environment of the macrophage, and to resist potent antibacterial molecules such as reactive oxygen species (ROS). Thus, understanding mycobacterial resistance mechanisms against ROS may contribute to the developmen...

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Detalles Bibliográficos
Autores principales: Mestre, Olga, Hurtado-Ortiz, Raquel, Dos Vultos, Tiago, Namouchi, Amine, Cimino, Mena, Pimentel, Madalena, Neyrolles, Olivier, Gicquel, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540035/
https://www.ncbi.nlm.nih.gov/pubmed/23320090
http://dx.doi.org/10.1371/journal.pone.0053486