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High Throughput Phenotypic Selection of Mycobacterium tuberculosis Mutants with Impaired Resistance to Reactive Oxygen Species Identifies Genes Important for Intracellular Growth
Mycobacterium tuberculosis has the remarkable capacity to survive within the hostile environment of the macrophage, and to resist potent antibacterial molecules such as reactive oxygen species (ROS). Thus, understanding mycobacterial resistance mechanisms against ROS may contribute to the developmen...
Autores principales: | Mestre, Olga, Hurtado-Ortiz, Raquel, Dos Vultos, Tiago, Namouchi, Amine, Cimino, Mena, Pimentel, Madalena, Neyrolles, Olivier, Gicquel, Brigitte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540035/ https://www.ncbi.nlm.nih.gov/pubmed/23320090 http://dx.doi.org/10.1371/journal.pone.0053486 |
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