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Spatial Promoter Recognition Signatures May Enhance Transcription Factor Specificity in Yeast

The short length and high degeneracy of sites recognized by DNA-binding transcription factors limit the amount of information they can carry, and individual sites are rarely sufficient to mediate the regulation of specific targets. Computational analysis of microbial genomes has suggested that many...

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Detalles Bibliográficos
Autores principales: Lusk, Richard W., Eisen, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540036/
https://www.ncbi.nlm.nih.gov/pubmed/23320104
http://dx.doi.org/10.1371/journal.pone.0053778