Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI

Nalbuphine, an agonist-antagonist kappa-opioid, produces brief analgesia followed by enhanced pain/hyperalgesia in male postsurgical patients. However, it produces profound analgesia without pain enhancement when co-administration with low dose naloxone. To examine the effect of nalbuphine or nalbup...

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Detalles Bibliográficos
Autores principales: Gear, Robert, Becerra, Lino, Upadhyay, Jaymin, Bishop, James, Wallin, Diana, Pendse, Gautam, Levine, Jon, Borsook, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540048/
https://www.ncbi.nlm.nih.gov/pubmed/23341872
http://dx.doi.org/10.1371/journal.pone.0050169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540048/
https://www.ncbi.nlm.nih.gov/pubmed/23341872
http://dx.doi.org/10.1371/journal.pone.0050169

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