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Delaying Reverse Transcription Does Not Increase Sensitivity of HIV-1 to Human TRIM5α
BACKGROUND: Because uncoating of the capsid is linked to reverse transcription, modifications that delay this process lead to the persistence in the cytoplasm of capsids susceptible to recognition by the human restriction factor TRIM5α (hTRIM5α). It is unknown, however, if increasing the time availa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540060/ https://www.ncbi.nlm.nih.gov/pubmed/23320071 http://dx.doi.org/10.1371/journal.pone.0052434 |