Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy

Neurosin is a protease that in vitro degrades α-synuclein, the main constituent of Lewy bodies found in brains of patients with synucleinopathy including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Several studies have reported reduced cerebrospinal fluid (CSF) levels of α-syn...

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Detalles Bibliográficos
Autores principales: Wennström, Malin, Surova, Yulia, Hall, Sara, Nilsson, Christer, Minthon, Lennart, Boström, Fredrik, Hansson, Oskar, Nielsen, Henrietta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540093/
https://www.ncbi.nlm.nih.gov/pubmed/23308173
http://dx.doi.org/10.1371/journal.pone.0053250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540093/
https://www.ncbi.nlm.nih.gov/pubmed/23308173
http://dx.doi.org/10.1371/journal.pone.0053250

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