p38 MAPK mediates calcium oxalate crystal-induced tight junction disruption in distal renal tubular epithelial cells

We examined whether p38 MAPK plays role in calcium oxalate monohydrate (COM) crystal-induced tight junction disruption. Polarized MDCK cells were pretreated with or without 20 μM SB239063 (p38 MAPK inhibitor) for 2-h, and then incubated with 100 μg/ml COM crystals for up to 48-h. Western blotting sh...

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Detalles Bibliográficos
Autores principales: Peerapen, Paleerath, Thongboonkerd, Visith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540397/
https://www.ncbi.nlm.nih.gov/pubmed/23304432
http://dx.doi.org/10.1038/srep01041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540397/
https://www.ncbi.nlm.nih.gov/pubmed/23304432
http://dx.doi.org/10.1038/srep01041

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