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p38 MAPK mediates calcium oxalate crystal-induced tight junction disruption in distal renal tubular epithelial cells
We examined whether p38 MAPK plays role in calcium oxalate monohydrate (COM) crystal-induced tight junction disruption. Polarized MDCK cells were pretreated with or without 20 μM SB239063 (p38 MAPK inhibitor) for 2-h, and then incubated with 100 μg/ml COM crystals for up to 48-h. Western blotting sh...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540397/ https://www.ncbi.nlm.nih.gov/pubmed/23304432 http://dx.doi.org/10.1038/srep01041 |