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Immune profiling with a Salmonella Typhi antigen microarray identifies new diagnostic biomarkers of human typhoid

Current serological diagnostic assays for typhoid fever are based on detecting antibodies against Salmonella LPS or flagellum, resulting in a high false-positive rate. Here we used a protein microarray containing 2,724 Salmonella enterica serovar Typhi antigens (>63% of proteome) and identified a...

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Detalles Bibliográficos
Autores principales: Liang, Li, Juarez, Silvia, Nga, Tran Vu Thieu, Dunstan, Sarah, Nakajima-Sasaki, Rie, Davies, D. Huw, McSorley, Stephen, Baker, Stephen, Felgner, Philip L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540400/
https://www.ncbi.nlm.nih.gov/pubmed/23304434
http://dx.doi.org/10.1038/srep01043