The Effect of D-(−)-arabinose on Tyrosinase: An Integrated Study Using Computational Simulation and Inhibition Kinetics

Tyrosinase is a ubiquitous enzyme with diverse physiologic roles related to pigment production. Tyrosinase inhibition has been well studied for cosmetic, medicinal, and agricultural purposes. We simulated the docking of tyrosinase and D-(−)-arabinose and found a binding energy of −4.5 kcal/mol for t...

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Detalles Bibliográficos
Autores principales: Liu, Hong-Jian, Ji, Sunyoung, Fan, Yong-Qiang, Yan, Li, Yang, Jun-Mo, Zhou, Hai-Meng, Lee, Jinhyuk, Wang, Yu-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540692/
https://www.ncbi.nlm.nih.gov/pubmed/23365724
http://dx.doi.org/10.1155/2012/731427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540692/
https://www.ncbi.nlm.nih.gov/pubmed/23365724
http://dx.doi.org/10.1155/2012/731427

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