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The Effect of D-(−)-arabinose on Tyrosinase: An Integrated Study Using Computational Simulation and Inhibition Kinetics
Tyrosinase is a ubiquitous enzyme with diverse physiologic roles related to pigment production. Tyrosinase inhibition has been well studied for cosmetic, medicinal, and agricultural purposes. We simulated the docking of tyrosinase and D-(−)-arabinose and found a binding energy of −4.5 kcal/mol for t...
Autores principales: | Liu, Hong-Jian, Ji, Sunyoung, Fan, Yong-Qiang, Yan, Li, Yang, Jun-Mo, Zhou, Hai-Meng, Lee, Jinhyuk, Wang, Yu-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540692/ https://www.ncbi.nlm.nih.gov/pubmed/23365724 http://dx.doi.org/10.1155/2012/731427 |
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