Encapsulation of factor IX–engineered mesenchymal stem cells in fibrinogen–alginate microcapsules enhances their viability and transgene secretion

Cell microencapsulation holds significant promise as a strategy for cellular therapies; however, inadequate survival and functionality of the enclosed cells limit its application in hemophilia treatment. Here, we evaluated the use of alginate-based microcapsules to enhance the viability and transgen...

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Detalles Bibliográficos
Autores principales: Sayyar, Bahareh, Dodd, Megan, Wen, Jianping, Ma, Shirley, Marquez-Curtis, Leah, Janowska-Wieczorek, Anna, Hortelano, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540750/
https://www.ncbi.nlm.nih.gov/pubmed/23316273
http://dx.doi.org/10.1177/2041731412462018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540750/
https://www.ncbi.nlm.nih.gov/pubmed/23316273
http://dx.doi.org/10.1177/2041731412462018

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