A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors

BACKGROUND: Ursolic acid is a promising anticancer agent. The current study aims to evaluate the single- and multiple-dose pharmacokinetics (PK) as well as the safety of ursolic acid nanoliposomes (UANL) in healthy volunteers and in patients with advanced solid tumors. METHODS: Twenty-four healthy v...

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Detalles Bibliográficos
Autores principales: Zhu, Zhongling, Qian, Zhengzi, Yan, Zhao, Zhao, Cuicui, Wang, Huaqing, Ying, Guoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540956/
https://www.ncbi.nlm.nih.gov/pubmed/23319864
http://dx.doi.org/10.2147/IJN.S38271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540956/
https://www.ncbi.nlm.nih.gov/pubmed/23319864
http://dx.doi.org/10.2147/IJN.S38271

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