Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation

The aim of this work was to establish a novel polymeric mixed micelle composed of Pluronic P105 and F127 copolymers loaded with the poorly soluble antitumor drug docetaxel (DTX) against Taxol-resistant non-small cell lung cancer. A central composite design was utilized to optimize the preparation pr...

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Detalles Bibliográficos
Autores principales: Chen, Liangcen, Sha, Xianyi, Jiang, Xinyi, Chen, Yanzuo, Ren, Qiuyue, Fang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540961/
https://www.ncbi.nlm.nih.gov/pubmed/23319859
http://dx.doi.org/10.2147/IJN.S38221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540961/
https://www.ncbi.nlm.nih.gov/pubmed/23319859
http://dx.doi.org/10.2147/IJN.S38221

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