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Codelivery of zoledronic acid and doublestranded RNA from core-shell nanoparticles

BACKGROUND: Zoledronic acid, an inhibitor of osteoclast-mediated bone resorption, has been shown to have both direct and indirect antitumor activity. However, its use in extraskeletal malignancy is limited due to rapid uptake and accumulation within bone. Polyinosinic acid-polycytidylic acid [poly (...

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Detalles Bibliográficos
Autores principales: Chen, Li, Ding, Yunfei, Wang, Yongzhong, Liu, Xingrong, Babu, RJ, Ravis, WR, Yan, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540971/
https://www.ncbi.nlm.nih.gov/pubmed/23319865
http://dx.doi.org/10.2147/IJN.S38928