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Codelivery of zoledronic acid and doublestranded RNA from core-shell nanoparticles
BACKGROUND: Zoledronic acid, an inhibitor of osteoclast-mediated bone resorption, has been shown to have both direct and indirect antitumor activity. However, its use in extraskeletal malignancy is limited due to rapid uptake and accumulation within bone. Polyinosinic acid-polycytidylic acid [poly (...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540971/ https://www.ncbi.nlm.nih.gov/pubmed/23319865 http://dx.doi.org/10.2147/IJN.S38928 |