Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

Emerging studies indicate that metabolism of arachidonic acid through the 5-lipoxygenase (5-Lox) pathway plays a critical role in the survival of prostate cancer cells raising the possibility that 5-Lox can be targeted for an effective therapy of prostate cancer. Wedelolactone (WDL), a medicinal pla...

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Detalles Bibliográficos
Autores principales: SARVESWARAN, SIVALOKANATHAN, GAUTAM, SUBHASH C., GHOSH, JAGADANANDA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541032/
https://www.ncbi.nlm.nih.gov/pubmed/23076676
http://dx.doi.org/10.3892/ijo.2012.1664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541032/
https://www.ncbi.nlm.nih.gov/pubmed/23076676
http://dx.doi.org/10.3892/ijo.2012.1664

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