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Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage

BACKGROUND: The availability of over 3000 published genome sequences has enabled the use of comparative genomic approaches to drive the biological function discovery process. Classically, one used to link gene with function by genetic or biochemical approaches, a lengthy process that often took year...

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Detalles Bibliográficos
Autores principales: de Crécy-Lagard, Valérie, Forouhar, Farhad, Brochier-Armanet, Céline, Tong, Liang, Hunt, John F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541065/
https://www.ncbi.nlm.nih.gov/pubmed/23013770
http://dx.doi.org/10.1186/1745-6150-7-32