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DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice
BACKGROUND: Insulin-like growth factor 2 (Igf2) is a paternally expressed imprinted gene regulating fetal growth, playing an integral role in the development of many tissues including the brain. The parent-of-origin specific expression of Igf2 is largely controlled by allele-specific DNA methylation...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541153/ https://www.ncbi.nlm.nih.gov/pubmed/23216893 http://dx.doi.org/10.1186/1756-6606-5-42 |