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Kalrn plays key roles within and outside of the nervous system

BACKGROUND: The human KALRN gene, which encodes a complex, multifunctional Rho GDP/GTP exchange factor, has been linked to cardiovascular disease, psychiatric disorders and neurodegeneration. Examination of existing Kalrn knockout mouse models has focused only on neuronal phenotypes. However, Kaliri...

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Detalles Bibliográficos
Autores principales: Mandela, Prashant, Yankova, Maya, Conti, Lisa H, Ma, Xin-Ming, Grady, James, Eipper, Betty A, Mains, Richard E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541206/
https://www.ncbi.nlm.nih.gov/pubmed/23116210
http://dx.doi.org/10.1186/1471-2202-13-136