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Kalrn plays key roles within and outside of the nervous system
BACKGROUND: The human KALRN gene, which encodes a complex, multifunctional Rho GDP/GTP exchange factor, has been linked to cardiovascular disease, psychiatric disorders and neurodegeneration. Examination of existing Kalrn knockout mouse models has focused only on neuronal phenotypes. However, Kaliri...
Autores principales: | Mandela, Prashant, Yankova, Maya, Conti, Lisa H, Ma, Xin-Ming, Grady, James, Eipper, Betty A, Mains, Richard E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541206/ https://www.ncbi.nlm.nih.gov/pubmed/23116210 http://dx.doi.org/10.1186/1471-2202-13-136 |
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