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Wnt3a induces exosome secretion from primary cultured rat microglia

BACKGROUND: Microglia, the immune effector cells of the CNS and the signaling molecule Wnt, both play critical roles in neurodevelopment and neurological disease. Here we describe the inducible release of exosomes from primary cultured rat microglia following treatment with recombinant carrier-free...

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Detalles Bibliográficos
Autores principales: Hooper, Claudie, Sainz-Fuertes, Ricardo, Lynham, Steven, Hye, Abdul, Killick, Richard, Warley, Alice, Bolondi, Cecilia, Pocock, Jennifer, Lovestone, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541220/
https://www.ncbi.nlm.nih.gov/pubmed/23173708
http://dx.doi.org/10.1186/1471-2202-13-144