Cargando…

Wnt3a induces exosome secretion from primary cultured rat microglia

BACKGROUND: Microglia, the immune effector cells of the CNS and the signaling molecule Wnt, both play critical roles in neurodevelopment and neurological disease. Here we describe the inducible release of exosomes from primary cultured rat microglia following treatment with recombinant carrier-free...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hooper, Claudie, Sainz-Fuertes, Ricardo, Lynham, Steven, Hye, Abdul, Killick, Richard, Warley, Alice, Bolondi, Cecilia, Pocock, Jennifer, Lovestone, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541220/ https://www.ncbi.nlm.nih.gov/pubmed/23173708 http://dx.doi.org/10.1186/1471-2202-13-144

Ejemplares similares

Correction to: Wnt3a induces exosome secretion from primary cultured rat microglia
por: Hooper, Claudie, et al.
Publicado: (2020)

Alzheimer’s Disease, Diagnosis and the Need for Biomarkers
por: Hooper, Claudie, et al.
Publicado: (2008)

The GSK3 hypothesis of Alzheimer's disease
por: Hooper, Claudie, et al.
Publicado: (2008)

The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons
por: Hooper, Claudie, et al.
Publicado: (2007)

p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells
por: Hooper, Claudie, et al.
Publicado: (2007)

Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes
por: Lee, Sang H., et al.
Publicado: (2018)

Differential Stimulation of Pluripotent Stem Cell-Derived Human Microglia Leads to Exosomal Proteomic Changes Affecting Neurons
por: Mallach, Anna, et al.
Publicado: (2021)

Exosomes go with the Wnt
por: Koles, Kate, et al.
Publicado: (2012)

WNT signaling in microglia and the glioma microenvironment
por: Schulte, Gunnar
Publicado: (2015)

Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression
por: Fan, Cuiqin, et al.
Publicado: (2022)

Microglia, Alzheimer's Disease, and Complement
por: Crehan, Helen, et al.
Publicado: (2012)

Non–small cell lung cancer-derived exosomes promote proliferation, phagocytosis, and secretion of microglia via exosomal microRNA in the metastatic microenvironment
por: Chen, Peng, et al.
Publicado: (2022)

Tumor-secreted exosomal Wnt2B activates fibroblasts to promote cervical cancer progression
por: Liang, Luo-Jiao, et al.
Publicado: (2021)

Exosomes Secreted by Microglia During Virus Infection in the Central Nervous System Activate an Inflammatory Response in Bystander Cells
por: Luong, Nhungoc, et al.
Publicado: (2021)

Microglia as modulators of exosomal alpha-synuclein transmission
por: Xia, Yun, et al.
Publicado: (2019)

Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil
por: Sellers, Katherine J., et al.
Publicado: (2018)

Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression
por: Xian, Xian, et al.
Publicado: (2022)

Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
por: Yang, Yunying, et al.
Publicado: (2020)

Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH
por: Killick, R., et al.
Publicado: (2013)

Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99]
por: Killick, R., et al.
Publicado: (2013)

Signaling Pathways in Exosomes Biogenesis, Secretion and Fate
por: Urbanelli, Lorena, et al.
Publicado: (2013)

Alcohol Modulates the Biogenesis and Composition of Microglia-Derived Exosomes
por: Crenshaw, Brennetta J., et al.
Publicado: (2019)

Wnt Secretion and Gradient Formation
por: Solis, Gonzalo P., et al.
Publicado: (2013)

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice
por: Killick, Richard, et al.
Publicado: (2009)

Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture Methods
por: Yoo, Hyun-Jung, et al.
Publicado: (2022)

Protocol for assessing phagocytosis activity in cultured primary murine microglia
por: Layman, Elsie, et al.
Publicado: (2022)

Isolation of detergent resistant microdomains from cultured neurons: detergent dependent alterations in protein composition
por: Williamson, Ritchie, et al.
Publicado: (2010)

Exosomal MiRNA Transfer between Retinal Microglia and RPE
por: Morris, Dorothea R., et al.
Publicado: (2020)

Microglia Polarization: A Novel Target of Exosome for Stroke Treatment
por: Wan, Teng, et al.
Publicado: (2022)

Microglia depletion prevents lactation by inhibition of prolactin secretion
por: Csikós, Vivien, et al.
Publicado: (2023)

Secreted Wnt antagonists in scrub typhus
por: Ueland, Thor, et al.
Publicado: (2021)

The Roles of Secreted Wnt Ligands in Cancer
por: Werner, Johannes, et al.
Publicado: (2023)

Tridimensional cell culture of dermal fibroblasts promotes exosome-mediated secretion of extracellular matrix proteins
por: Clément, Vincent, et al.
Publicado: (2022)

TREM2 and microglia exosomes: a potential highway for pathological tau
por: Jain, Nimansha, et al.
Publicado: (2022)

Exosomes: secreted vesicles and intercellular communications
por: Théry, Clotilde
Publicado: (2011)

Rab35 drives exosome secretion
por: Short, Ben
Publicado: (2010)

Prediction of unconventional protein secretion by exosomes
por: Ras-Carmona, Alvaro, et al.
Publicado: (2021)

Protocol for Co-culture of Microglia with Axons
por: Fujita, Yuki, et al.
Publicado: (2020)

CWN-2/Wnt regulates SMDD axonal development
por: Sherry, Tessa, et al.
Publicado: (2020)

WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts
por: Działo, Edyta, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dh2gn3mr6l4hise9t3dncs9obo