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Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis

BACKGROUND: Although the etiology of PD remains unclear, increasing evidence has shown that oxidative stress plays an important role in its pathogenesis and that of other neurodegenerative disorders. NOX2, a cytochrome subunit of NOX, transports electrons across the plasma membrane to generate ROS,...

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Detalles Bibliográficos
Autores principales: Ye, Qinyong, Huang, Bixia, Zhang, Xiaodong, Zhu, Yuangui, Chen, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541259/
https://www.ncbi.nlm.nih.gov/pubmed/23272707
http://dx.doi.org/10.1186/1471-2202-13-156