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Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury

Developing new pharmacotherapies for traumatic brain injury (TBI) requires elucidation of the neuroprotective mechanisms of many structurally and functionally diverse compounds. To test our hypothesis that diverse neuroprotective drugs similarly affect common gene targets after TBI, we compared the...

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Detalles Bibliográficos
Autores principales: Hellmich, Helen L., Rojo, Daniel R., Micci, Maria-Adelaide, Sell, Stacy L., Boone, Deborah R., Crookshanks, Jeanna M., DeWitt, Douglas S., Masel, Brent E., Prough, Donald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541279/
https://www.ncbi.nlm.nih.gov/pubmed/23326402
http://dx.doi.org/10.1371/journal.pone.0053230