Involvement of autophagy and mitochondrial dynamics in determining the fate and effects of irreparable mitochondrial DNA damage

Mitochondrial DNA (mtDNA) is different in many ways from nuclear DNA. A key difference is that certain types of DNA damage are not repaired in the mitochondrial genome. What, then, is the fate of such damage? What are the effects? Both questions are important from a health perspective because irrepa...

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Detalles Bibliográficos
Autores principales: Meyer, Joel N., Bess, Amanda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Autophagic Punctum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541291/
https://www.ncbi.nlm.nih.gov/pubmed/22929123
http://dx.doi.org/10.4161/auto.21741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541291/
https://www.ncbi.nlm.nih.gov/pubmed/22929123
http://dx.doi.org/10.4161/auto.21741

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