Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions

Alzheimer disease (AD) is sometimes referred to as type III diabetes because of the shared risk factors for the two disorders. Insulin resistance, one of the major components of type II diabetes mellitus (T2DM), is a known risk factor for AD. Insulin resistance increases amyloid-β peptide (Aβ) gener...

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Detalles Bibliográficos
Autores principales: Son, Sung Min, Song, Hyundong, Byun, Jayoung, Park, Kyong Soo, Jang, Hak Chul, Park, Young Joo, Mook-Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Autophagic Punctum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541299/
https://www.ncbi.nlm.nih.gov/pubmed/22931791
http://dx.doi.org/10.4161/auto.21861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541299/
https://www.ncbi.nlm.nih.gov/pubmed/22931791
http://dx.doi.org/10.4161/auto.21861

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