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Lysosomal secretion of Flightless I upon injury has the potential to alter inflammation

Intracellular Flightless I (Flii), a gelsolin family member, has been found to have roles modulating actin regulation, transcriptional regulation and inflammation. In vivo Flii can regulate wound healing responses. We have recently shown that a pool of Flii is secreted by fibroblasts and macrophages...

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Detalles Bibliográficos
Autores principales: Cowin, Allison J., Lei, Nazi, Franken, Linda, Ruzehaji, Nadira, Offenhäuser, Carolin, Kopecki, Zlatko, Murray, Rachael Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541319/
https://www.ncbi.nlm.nih.gov/pubmed/23336022
http://dx.doi.org/10.4161/cib.21928