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Death or secretion? The demise of a plausible assumption about CSF-tau in Alzheimer Disease?
Our recent identification of an exosomal route for tau protein secretion(1) marks a key similarity between tau and other aggregation-prone proteins implicated in neurodegenerative disease pathogenesis and is to some extent congruent with the popular idea that tau pathology spreads between neurons vi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541332/ https://www.ncbi.nlm.nih.gov/pubmed/23740221 http://dx.doi.org/10.4161/cib.21437 |