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Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells

BACKGROUND: Bupivacaine-induced neurotoxicity has been shown to occur through apoptosis. Recently, bupivacaine was shown to elicit reactive oxygen species (ROS) production and induce apoptosis accompanied by activation of p38 mitogen-activated protein kinase (MAPK) in a human neuroblastoma cell line...

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Detalles Bibliográficos
Autores principales: Harato, Misako, Huang, Lei, Kondo, Fumio, Tsunekawa, Koji, Feng, Guo-Gang, Fan, Jun-Hua, Ishikawa, Naohisa, Fujiwara, Yoshihiro, Okada, Shoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541351/
https://www.ncbi.nlm.nih.gov/pubmed/23227925
http://dx.doi.org/10.1186/1471-2202-13-149