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Gly1057Asp polymorphism of insulin receptor substrate-2 is associated with coronary artery disease in the Taiwanese population

BACKGROUND: Gly1057Asp polymorphism in insulin receptor substrate (IRS)-2 is related to insulin resistance and diabetes mellitus (DM), which both contribute to the pathogenesis of coronary artery disease (CAD). Hence, we hypothesize that Gly1057Asp polymorphism in IRS-2 is associated with CAD. METHO...

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Detalles Bibliográficos
Autores principales: Chan, Shih-Hung, Chen, Jyh-Hong, Li, Yi-Heng, Tsai, Liang-Miin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541354/
https://www.ncbi.nlm.nih.gov/pubmed/23216712
http://dx.doi.org/10.1186/1423-0127-19-100