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Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression

BACKGROUND: Phenotypic evolution in animals is thought to be driven in large part by differences in gene expression patterns, which can result from sequence changes in cis-regulatory elements (cis-changes) or from changes in the expression pattern or function of transcription factors (trans-changes)...

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Detalles Bibliográficos
Autores principales: Ariza-Cosano, Ana, Visel, Axel, Pennacchio, Len A, Fraser, Hunter B, Gómez-Skarmeta, José Luis, Irimia, Manuel, Bessa, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541358/
https://www.ncbi.nlm.nih.gov/pubmed/23253453
http://dx.doi.org/10.1186/1471-2164-13-713