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Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression
BACKGROUND: Phenotypic evolution in animals is thought to be driven in large part by differences in gene expression patterns, which can result from sequence changes in cis-regulatory elements (cis-changes) or from changes in the expression pattern or function of transcription factors (trans-changes)...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541358/ https://www.ncbi.nlm.nih.gov/pubmed/23253453 http://dx.doi.org/10.1186/1471-2164-13-713 |