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BRCA1 mRNA Expression as a Predictive and Prognostic Marker in Advanced Esophageal Squamous Cell Carcinoma Treated with Cisplatin- or Docetaxel-Based Chemotherapy/Chemoradiotherapy

BACKGROUND: The molecular backgrounds that determine therapeutic effectiveness in esophageal cancer remain largely unknown. Breast cancer susceptibility gene 1 (BRCA1) expression has been found to switch the response to cisplatin- or paclitaxel-based chemotherapy. It remains unclear how variations i...

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Detalles Bibliográficos
Autores principales: Gao, Yong, Zhu, Jing, Zhang, Xiaohui, Wu, Qingquan, Jiang, Shaoning, Liu, Yangqing, Hu, Zhibin, Liu, Baorui, Chen, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541365/
https://www.ncbi.nlm.nih.gov/pubmed/23326344
http://dx.doi.org/10.1371/journal.pone.0052589