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Interaction of G-Protein βγ Complex with Chromatin Modulates GPCR-Dependent Gene Regulation

Heterotrimeric G-protein signal transduction initiated by G-protein-coupled receptors (GPCRs) in the plasma membrane is thought to propagate through protein-protein interactions of subunits, Gα and Gβγ in the cytosol. In this study, we show novel nuclear functions of Gβγ through demonstrating intera...

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Detalles Bibliográficos
Autores principales: Bhatnagar, Anushree, Unal, Hamiyet, Jagannathan, Rajaganapathi, Kaveti, Suma, Duan, Zhong-Hui, Yong, Sandro, Vasanji, Amit, Kinter, Michael, Desnoyer, Russell, Karnik, Sadashiva S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541368/
https://www.ncbi.nlm.nih.gov/pubmed/23326349
http://dx.doi.org/10.1371/journal.pone.0052689