Prime-Boost Immunization of Rabbits with HIV-1 gp120 Elicits Potent Neutralization Activity against a Primary Viral Isolate

Development of a vaccine for HIV-1 requires a detailed understanding of the neutralizing antibody responses that can be experimentally elicited to difficult-to-neutralize primary isolates. Rabbits were immunized with the gp120 subunit of HIV-1 JR-CSF envelope (Env) using a DNA-prime protein-boost re...

Descripción completa

Detalles Bibliográficos
Autores principales: Narayan, Kristin M., Agrawal, Nitish, Du, Sean X., Muranaka, Janelle E., Bauer, Katherine, Leaman, Daniel P., Phung, Pham, Limoli, Kay, Chen, Helen, Boenig, Rebecca I., Wrin, Terri, Zwick, Michael B., Whalen, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541383/
https://www.ncbi.nlm.nih.gov/pubmed/23326351
http://dx.doi.org/10.1371/journal.pone.0052732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541383/
https://www.ncbi.nlm.nih.gov/pubmed/23326351
http://dx.doi.org/10.1371/journal.pone.0052732

Ejemplares similares