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Two-step nanoprecipitation for the production of protein-loaded PLGA nanospheres

One of the first methods to encapsulate drugs within polymer nanospheres was developed by Fessi and coworkers in 1989 and consisted of one-step nanoprecipitation based on solvent displacement. However, proteins are poorly encapsulated within polymer nanoparticles using this method because of their l...

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Detalles Bibliográficos
Autores principales: Morales-Cruz, Moraima, Flores-Fernández, Giselle M., Morales-Cruz, Myreisa, Orellano, Elsie A., Rodriguez-Martinez, José A., Ruiz, Mercedes, Griebenow, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541529/
https://www.ncbi.nlm.nih.gov/pubmed/23316451
http://dx.doi.org/10.1016/j.rinphs.2012.11.001