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Two-step nanoprecipitation for the production of protein-loaded PLGA nanospheres
One of the first methods to encapsulate drugs within polymer nanospheres was developed by Fessi and coworkers in 1989 and consisted of one-step nanoprecipitation based on solvent displacement. However, proteins are poorly encapsulated within polymer nanoparticles using this method because of their l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541529/ https://www.ncbi.nlm.nih.gov/pubmed/23316451 http://dx.doi.org/10.1016/j.rinphs.2012.11.001 |