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Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy

Since the ability of cancer cells to evade apoptosis often limits the efficacy of radiotherapy and chemotherapy, autophagy is emerging as an alternative target to promote cell death. Therefore, we wondered whether Rottlerin, a natural polyphenolic compound with antiproliferative effects in several c...

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Detalles Bibliográficos
Autores principales: Torricelli, Claudia, Salvadori, Sara, Valacchi, Giuseppe, Souček, Karel, Slabáková, Eva, Muscettola, Michela, Volpi, Nila, Maioli, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541534/
https://www.ncbi.nlm.nih.gov/pubmed/23320042
http://dx.doi.org/10.1155/2012/980658