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Hyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response

Plasma secretion of acid sphingomyelinase is a hallmark of cellular stress response resulting in the formation of membrane embedded ceramide-enriched lipid rafts and the reorganization of receptor complexes. Consistently, decompartmentalization of ceramide formation from inert sphingomyelin has been...

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Detalles Bibliográficos
Autores principales: Jbeily, Nayla, Suckert, Iris, Gonnert, Falk A., Acht, Benedikt, Bockmeyer, Clemens L., Grossmann, Sascha D., Blaess, Markus F., Lueth, Anja, Deigner, Hans-Peter, Bauer, Michael, Claus, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541704/
https://www.ncbi.nlm.nih.gov/pubmed/23230083
http://dx.doi.org/10.1194/jlr.M031625