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Hyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response
Plasma secretion of acid sphingomyelinase is a hallmark of cellular stress response resulting in the formation of membrane embedded ceramide-enriched lipid rafts and the reorganization of receptor complexes. Consistently, decompartmentalization of ceramide formation from inert sphingomyelin has been...
Autores principales: | Jbeily, Nayla, Suckert, Iris, Gonnert, Falk A., Acht, Benedikt, Bockmeyer, Clemens L., Grossmann, Sascha D., Blaess, Markus F., Lueth, Anja, Deigner, Hans-Peter, Bauer, Michael, Claus, Ralf A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular
Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541704/ https://www.ncbi.nlm.nih.gov/pubmed/23230083 http://dx.doi.org/10.1194/jlr.M031625 |
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