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A Phase II, Randomized, Safety and Immunogenicity Study of a Re-Derived, Live-Attenuated Dengue Virus Vaccine in Healthy Adults

Two formulations of a new live tetravalent dengue virus (DENV) vaccine produced using re-derived master seeds from a precursor vaccine and that same precursor vaccine as a control were compared in a placebo-controlled, randomized, observer-blind, phase II trial of 86 healthy adults. Two vaccine dose...

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Detalles Bibliográficos
Autores principales: Thomas, Stephen J., Eckels, Kenneth H., Carletti, Isabelle, De La Barrera, Rafael, Dessy, Francis, Fernandez, Stefan, Putnak, Robert, Toussaint, Jean-Francois, Sun, Wellington, Bauer, Kristen, Gibbons, Robert V., Innis, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541749/
https://www.ncbi.nlm.nih.gov/pubmed/23208878
http://dx.doi.org/10.4269/ajtmh.2012.12-0361