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Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy
Bone morphogenetic proteins (BMPs) are important extracellular cytokines that play critical roles in embryogenesis and tissue homeostasis. BMPs signal via transmembrane type I and type II serine/threonine kinase receptors and intracellular Smad effector proteins. BMP signaling is precisely regulated...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541930/ https://www.ncbi.nlm.nih.gov/pubmed/22752156 http://dx.doi.org/10.1007/s00018-012-1054-x |