Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy

Bone morphogenetic proteins (BMPs) are important extracellular cytokines that play critical roles in embryogenesis and tissue homeostasis. BMPs signal via transmembrane type I and type II serine/threonine kinase receptors and intracellular Smad effector proteins. BMP signaling is precisely regulated...

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Detalles Bibliográficos
Autores principales: Shi, SongTing, de Gorter, David J. J., Hoogaars, Willem M. H., ’t Hoen, Peter A. C., ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541930/
https://www.ncbi.nlm.nih.gov/pubmed/22752156
http://dx.doi.org/10.1007/s00018-012-1054-x

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