Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function

RNA-binding proteins CUG-binding protein 1 (CUGBP1) and HuR are highly expressed in epithelial tissues and modulate the stability and translation of target mRNAs. Here we present evidence that CUGBP1 and HuR jointly regulate the translation of occludin and play a crucial role in the maintenance of t...

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Detalles Bibliográficos
Autores principales: Yu, Ting-Xi, Rao, Jaladanki N., Zou, Tongtong, Liu, Lan, Xiao, Lan, Ouyang, Miao, Cao, Shan, Gorospe, Myriam, Wang, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541967/
https://www.ncbi.nlm.nih.gov/pubmed/23155001
http://dx.doi.org/10.1091/mbc.E12-07-0531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541967/
https://www.ncbi.nlm.nih.gov/pubmed/23155001
http://dx.doi.org/10.1091/mbc.E12-07-0531

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