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Tumorigenesis role and clinical significance of DJ-1, a negative regulator of PTEN, in supraglottic squamous cell carcinoma

BACKGROUND: DJ-1 can induce the tumor cell proliferation and invasion via down-regulating PTEN in many malignant tumors, and correlated to prognostic significance. However, the tumorigenesis role and clinical significance of DJ-1 in supraglottic squamous cell carcinoma (SSCC) is unclear. We aimed to...

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Detalles Bibliográficos
Autores principales: Zhu, Xiao-Lin, Wang, Zhang-Feng, Lei, Wen-Bin, Zhuang, Hui-Wen, Hou, Wei-Jian, Wen, Yi-Hui, Wen, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541992/
https://www.ncbi.nlm.nih.gov/pubmed/23151319
http://dx.doi.org/10.1186/1756-9966-31-94