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Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice

BACKGROUND: Epicutaneous immunotherapy (EPIT) on intact skin with an epicutaneous delivery system has already been used in preclinical and clinical studies. In epicutaneous vaccination and immunotherapy, the stripping of skin before application of the allergen is suggested to facilitate the passage...

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Detalles Bibliográficos
Autores principales: Mondoulet, Lucie, Dioszeghy, Vincent, Puteaux, Emilie, Ligouis, Mélanie, Dhelft, Véronique, Letourneur, Franck, Dupont, Christophe, Benhamou, Pierre-Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542018/
https://www.ncbi.nlm.nih.gov/pubmed/23140259
http://dx.doi.org/10.1186/2045-7022-2-22