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Cyclophilin A secreted from fibroblast-like synoviocytes is involved in the induction of CD147 expression in macrophages of mice with collagen-induced arthritis

BACKGROUND: Cyclophilin A (CypA), a member of the immunophilin family, is a ubiquitously distributed intracellular protein. Recent studies have shown that CypA is secreted by cells in response to inflammatory stimuli. Elevated levels of extracellular CypA and its receptor, CD147 have been detected i...

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Detalles Bibliográficos
Autores principales: Nishioku, Tsuyoshi, Dohgu, Shinya, Koga, Mitsuhisa, Machida, Takashi, Watanabe, Takuya, Miura, Teppei, Tsumagari, Kousuke, Terasawa, Mariko, Yamauchi, Atsushi, Kataoka, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542031/
https://www.ncbi.nlm.nih.gov/pubmed/23167819
http://dx.doi.org/10.1186/1476-9255-9-44